DelveInsight’s, “Cervical Cancer Pipeline Insight” report provides comprehensive insights about 70+ companies and 70+ pipeline drugs in Cervical Cancer pipeline landscape. It covers the Cervical Cancer pipeline drug profiles, including clinical and nonclinical stage products. It also covers the Cervical Cancer therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.
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Key Takeaways from the Cervical Cancer Pipeline Report
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Cervical Cancer Emerging Drugs Profile
Axalimogene filolisbac is a type of cancer vaccine being developed as immunotherapy that attacks HPV-associated cancers such as cervical cancers. It works by alerting the body’s immune system to the presence of cancer, stimulating the body’s natural defenses to attack the cancer. Axalimogene filolisbac is given intravenously and is being developed for the treatment of persistent, recurrent, or metastatic, squamous or non-squamous cell cervical cancer in patients who progress beyond first-li Phase III Study of ADXS11-001 Administered Following Chemoradiation as Adjuvant Treatment for High Risk Locally Advanced Cervical Cancer: AIM2CERV ne therapy. If licensed, Axalimogene filolisbac will offer a new treatment option for this patient group.
Camrelizumab (AiRuiKa™), a programmed cell death 1 (PD-1) inhibitor being developed by Jiangsu Hengrui Medicine Co. Ltd, recently received conditional approval in China for the treatment of relapsed or refractory classical Hodgkin lymphoma. The drug is also being investigated as a treatment for various other malignancies, including B cell lymphoma, oesophageal squamous cell carcinoma, gastric/gastroesophageal junction cancer, hepatocellular carcinoma, nasopharyngeal cancer and non-squamous, non-small cell lung cancer. The drug is currently being evaluated in Phase III clinical trial for the treatment of cervical cancer.
Cadonilimab (AK104) is a novel, potential next-generation, first-in-class bi-specific PD-1/CTLA-4 immuno-oncology backbone drug independently developed by the Company, and its major indications include liver cancer, cervical cancer, lung cancer, gastric cancer, esophageal squamous cell cancer and nasopharyngeal carcinoma. The preliminary research data of cervical cancer, gastric cancer and other tumors shows that, as compared with the combination therapy of PD-1 and CTLA-4, Cadonilimab has much lower toxicity and demonstrated promising safety profile and efficacy. In September 2020, National Medical Products Administration (the NMPA) of China has officially accepted the new drug application for the world’s first-in-class Cadonilimab (PD-1/CTLA-4 bi-specific antibody, research and development code: AK104) for the treatment of relapsed or metastatic cervical cancer, which has received priority review.
A drug that binds to the protein PD-L1 to help immune cells kill cancer cells better and is used to treat different types of cancer. Durvalumab is used alone or with other drugs to treat adults with certain types of extensive-stage small cell lung cancer or stage III non-small cell lung cancer. It is also being studied in the treatment of other types of cancer. Durvalumab may block PD-L1 and help the immune system kill cancer cells. It is a type of monoclonal antibody and a type of immune checkpoint inhibitor. A Phase III clinical trial is being conducted for durvalumab to treat patients with cervical cancer.
HLX10, a novel recombinant humanised anti-programmed cell death protein 1 (PD-1) mAb independently developed by Henlius, has the potential to treat a variety of solid tumours. HLX10 has exhibited better pharmacokinetics, pharmacodynamics properties, favourable safety, tolerability profile and anti-tumor activity in preclinical and early clinical research studies. It is currently being investigated in Phase II stage of development to provide the potential treatment for cervical cancer.
The Cervical Cancer pipeline report provides insights into
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Cervical Cancer Companies
Regeneron Pharmaceuticals, Jiangsu Hengrui Medicine, Akeso Biopharma, Celgene/MedImmune, Henlix Biotech, Zeria, Advaxis, AnGes, Advenchen Laboratories/Jiangsu Chia Tai Tianqing Pharmaceutical, Valent recombinant vaccine – National Vaccine and Serum Institute, Xiamen Innovax Biotech, Genentech, Bristol-Myers Squibb, Ono Pharmaceuticals, InnoMab, BeiGene, Agenus/Ludwig Institute for Cancer Research, EMD Serono, Merck, Apollomics, Immunitor, Arcus Biosciences, Guangzhou Gloria Biosciences, Taiho Pharmaceutical, Innovent Biologics, Clovis Oncology, Janssen, GlaxoSmithKline, Iovance Biotherapeutics and others.
Cervical Cancer pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as
Cervical Cancer Products have been categorized under various Molecule types such as
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Scope of the Cervical Cancer Pipeline Report
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